Triclocarban
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
10g | $600 | To Be Confirmed |
25g | $1150 | To Be Confirmed |
50g | $1725 | To Be Confirmed |
Cat #: V5238 CAS #: 101-20-2 Purity ≥ 98%
Description: Triclocarban (3,4,4′-Trichlorocarbanilide) is an antimicrobial / antibacterial compound that is widely used in personal cleaning / personal care products.
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- Physicochemical and Storage Information
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- Related Biological Data
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Molecular Weight (MW) | 315.58 |
---|---|
Molecular Formula | C₁₃H₉Cl₃N₂O |
CAS No. | 101-20-2 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
SMILES Code | O=C(NC1=CC=C(Cl)C=C1)NC2=CC=C(Cl)C(Cl)=C2 |
Synonyms | Triclocarban |
Protocol | In Vitro | Triclocarban (300 nM) potentiates the cytotoxicity of 300 µM H2O2 in rat thymocytes. Triclocarban (300 nM) does not increase the population of death cells, it facilitates the process of cell death induced by H2O2, resulting in further increase in the population of dead cells. |
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In Vivo | Triclocarban is absorbed significantly from soap used during showering in human subjects and that its Cmax in their whole blood ranges from 23 nM to 530 nM. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 3.1688 mL | 15.8438 mL | 31.6877 mL | 63.3754 mL |
5mM | 0.6338 mL | 3.1688 mL | 6.3375 mL | 12.6751 mL |
10mM | 0.3169 mL | 1.5844 mL | 3.1688 mL | 6.3375 mL |
20mM | 0.1584 mL | 0.7922 mL | 1.5844 mL | 3.1688 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.