TPPB is a novel, potent and cell-permeable benzolactam-derived protein kinase C (PKC) activator (Ki = 11.9 nM) wuth neuroprotective effects.

Verbascoside (Acteoside; Kusaginin; TJC-160), a natural product isolated from Lantana camara, is novel and potent inhibitor of the Oligomerization of Pneumolysin.

LXS196 is a novel, potent, selective and orally bioactive inhibitor of protein kinase C (PKC) with IC50 values of 1.9 nM, 0.4 nM and 3.1 μM for PKCα, PKCθ and GSK3β, respectively.

R59022 (R-59022; DKGI-I) is a novel and potent DGKalpha inhibitor and serotonin receptor antagonist.

Chelerythrine is a novel and potent alkaloid.

CMPD101 is a novel, potent and selective inhibitor of G-protein coupled receptor kinase 2 and 3 (GRK2/GRK3) with IC50 values of 35 and 32 nM for GRK2 and GRK3, respectively.

Ruboxistaurin HCl, the hydrochloride salt of Ruboxistaurin (LY-333531; LY333531), is a novel, potent and specific inhibitor of PKCβ (protein kinase C) with diabetic effects.

Staurosporine (formerly also known as antibiotic AM-2282; CCRIS 3272; CGP 41251 or STS) is a naturally occuring, potent and non-selective PKC inhibitor with anti-fungal to anti-hypertensive effects.

Myricitrin (Myricitroside), a naturally occurring flavonoid compound isolated from the root bark of Myrica cerifera, is a bioactive compound which exerts antinociceptive effects.

Ro 31-8220 mesylate (RO31-8220; BIM IX; RO-31-8220; Bisindolylmaleimide IX; RO-318220), the mesylate salt of Ro 31-8220, is a novel and potent pan-PKC inhibitor with potential anticancer activity.