IRAK4 inhibitor-1 is a novel and potent inhibitor of Interleukin-1 receptor-associated kinase 4 (IRAK4) which is the most upstream kinase in Toll/Interleukin-1 receptor (TIR) signaling pathway. IRAK4 inhibitors have the therapeutic potential for treating autoimmune disease (e.g. rheumatoid arthritis- RA) and cancer.

TCS-2210 is a neuronal differentiation inducer in MSCs (mesenchymal stem cells ).

BMS 905 is a novel and potent Dual Antagonist of Toll-like Receptors 7 and 8 (TLR7/8),Control of this unintended activation via inhibition of TLR7/8 signaling holds promise for the treatment of diseases such as psoriasis, arthritis, and lupus.

SRI 37330 is a novel and potent inhibitor of TXNIP expression.

AZD7762 HCl (AZD-7762) is a novel, potent, selective, ATP-competitive, and synthetic small molecule checkpoint kinase (Chk) inhibitor with anticancer activity. It has an IC50 of 5 nM for Chk1. AZD-7762 has potential chemosensitizing activity by binding to and inhibits Chks, which may prevent cell cycle arrest and subsequent nucleotide excision repair in DNA-damaged tumor cells, […]

ML095 HCL (also known as MLS-0315848 HCL or CID-25067483 HCL) is a novel and potent PLAP(placental alkaline phosphatase) inhibitor. IC50 = 2.1 μM for PLAP, IC50>100 μM for TNAP and IC50 =53 μM for IAP.

SC-10914 (SC10914) is a novel and highly potent PARP inhibitor (IC50 = 7.87 nM) with anticancer activity. It has favorabler pharmacokinetic profiles and thus has the potential to be used for the treatment of treatment of BRCA1/2 deficient cancers.

Gramicidin S is an anttiboitics.Gramicidin S and melittin are potential anti-viral therapeutic peptides to treat SARS-CoV-2 infection.

Menaquinone-7 (also known as Vitamin K2-7; Vitamin K2(35); Vitamin MK-7), a class of K2-vitamin homologs, is originally discovered as a potent anti-hemorrhagic factors. Menaquinone-7 is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins . Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in […]

SR12343 is a potent tumor necrosis factor α (TNF-α) inhibitor