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SC10914

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SC10914
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10mg$1003-6 Days
25mg$1503-6 Days
50mg$2503-6 Days
100mg$4003-6 Days
250mg$6803-6 Days
500mg$10003-6 Days
email: [email protected]        [email protected]

Cat #: V2487 CAS #: 76985-08-5 (free base) Purity ≥ 99%

Description: SC-10914 (SC10914) is a novel and highly potent PARP inhibitor (IC50 = 7.87 nM) with anticancer activity. It has favorabler pharmacokinetic profiles and thus has the potential to be used for the treatment of treatment of BRCA1/2 deficient cancers.

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CAS No.76985-08-5 (free base)
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
 
=
Concentration
 
×
Volume
 
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
 
×
 
Volume(start)
V1
 
=
 
Concentration(final)
C2
 
×
 
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O
Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.