FTO inhibitor 1 (first disclosed in WO 2018157842) is a novel and potent FTO (fat-mass- and obesity-associated protein) inhibitor with the potential to be used for treatment of leukemia. FTO is overexpressed in certain subtypes of AMLs and promotes leukemogenesis.

Tenovin2 is a bioactive compound.

3-Methyl-3-buten-1-ol ,also known as NSC 12267 or isoprenol, is a pharmaceutical intermediates

MK571, also known as L660711, is a potent and selective competitive inhibitor of [3H]leukotriene D4 binding in guinea pig (Ki value, 0.22 nM) and human (Ki value, 2.1 nM) lung membranes but is essentially inactive versus [3H]leukotriene C4 binding (IC50 value in guinea pig lung, 23 microM). Reference: Pharmacology of L-660,711 (MK-571): a novel potent […]

CRT0066101 is a novel and potent PRKDs inhibitor.

TRISALICYLIC ACID is a bioactive molecule.

Pradefovir (formerly known as Remofovir, ICN-2001-3, MB-06866, MB-6866; ICN-20013) is an RTI (reverse transcriptase) inhibitor that has the potential for the treatment of chronic HBV infection. Pradefovir is prodrug of adefovir that is designed to target liver. Pradefovir can be activated to PMEA (9-(2-phosphonylmethoxyethyl)adenine ) in human liver microsomes with with a Km of 60 […]

Leniolisib phosphate (formerly known as CDZ173 phosphate; Joenja) is a novel, potent and selective PI3K (phosphatidylinositol 3-kinase inhibitor) inhibitor with IC50 values of 0.244, 0.424, 2.23 and 0.011 μM for PI3Kα, PI3Kβ, PI3Kγ and PI3Kδ, respectively. It is currently in phase II/III clinical trials for the treatment of immunodeficiency disorders. Oral leniolisib led to a […]

Phenylbis phosphine oxide is a bioactive molecole.

AI 10-47 is a novel and potent inhibitor of CBFβ-RUNX binding( IC50 =3.2 μM).