This product is for research use only, not for human use. We do not sell to patients.
| Size | Price | Stock |
|---|---|---|
| 10mg | $135 | To Be Confirmed |
| 25mg | $210 | To Be Confirmed |
| 50mg | $310 | To Be Confirmed |
| 100mg | $479 | To Be Confirmed |
| 250mg | $830 | To Be Confirmed |
| 500mg | $1350 | To Be Confirmed |
: Cat #: V4348 CAS #: 1246094-78-9 Purity ≥ 98%
Description: AZD7762 HCl (AZD-7762) is a novel, potent, selective, ATP-competitive, and synthetic small molecule checkpoint kinase (Chk) inhibitor with anticancer activity. It has an IC50 of 5 nM for Chk1. AZD-7762 has potential chemosensitizing activity by binding to and inhibits Chks, which may prevent cell cycle arrest and subsequent nucleotide excision repair in DNA-damaged tumor cells, resulting in tumor cell apoptosis. This agent may enhance the cytotoxicity of DNA-damaging agents. Chks are protein kinases that regulate either G1/S or G2/M transitions in the cell cycle. In the presence of DNA damage or incomplete DNA replication, Chks become activated and initiate cell cycle arrest to allow DNA repair or the completion of DNA replication.
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| CAS No. | 1246094-78-9 |
|---|---|
| Storage | -20℃ for 3 years in powder form |
| -80℃ for 2 years in solvent |
This equation is commonly abbreviated as: C1 V1 = C2 V2
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.