Tolbutamide sodium (also known as HLS 831; trade names: Artosin, Diabetol, Orinase) is a potent and selective inhibitor of potassium channel, which is originally used as an oral hypoglycemic medication. The drug may be used for the management of type II diabetes. Tolbutamide has been reported to inhibit both the basal and the cyclic AMP-stimulated […]

L-NIL diHCl (dihydrochloride) is a novel and potent inhibitor of inducible nitric oxide synthase (iNOS) (IC50 = 3.3 μM for miNOS) with anti-inflammatory activity. L-NIL has an IC50 of 3.3 microM for miNOS compared to an IC50 of 92 microM for rat brain constitutive NOS indicating that L-NIL is 28-fold more selective for inducible NOS. […]

HDAC8-IN-2 is a novel and potent HDAC8 inhibitor

CL-316243 disodium (CL316243) is a novel and potent β3-adrenoceptor agonist with the potential for the treatment obesity, diabetes and urge urinary incontinence. It activates β3-adrenoceptor with a EC50 of 3 nM.

EMD-66684 is a novel and potent angiotensin II receptor antagonist

Niranthin is a natural product

Concanavalin A (con A) is a plant lectin refined from jack beans

CYM50769 is a novel and potent non-peptide antagonist of neuropeptide W and B receptor 1 (NPBWR1, GPR7).

Calcein is a novel and potent fluorescent dye.