Melevodopa HCl (ST-41769; ST 41769; trade name Levomet), the hydrochloride salt of Melevodopa which is the methyl ester and prodrug form of levodopa, is a dopaminergic agent used as an anti-Dyskinesia drug. It has also been used in combination with carbidopa for the treatment of PD/Parkinson’s disease.

TASIN-1 Hydrochloride (Truncated APC Selective INhibitor-1) is a nove, potent and selective small molecule inhibitor of mutant adenomatous polyposis coli (APC). It acts by selectively killing colorectal cancer cells that express truncated APC by reducing cellular cholesterol levels and inducing apoptotic cell death through the ER stress/ROS/JNK signaling in colon cancer cells. In two authentic […]

P7C3-A20 (P 7C3-A20; P7C3A20) is a P7C3 derivative that acts as a proneurogenic and neuroprotective agent with neuroprotective activity. P7C3-A20 displayed increased activity and an improved toxicity profile compared to P7C3. P7C3-A20 demonstrated greater proneurogenic efficacy than a wide spectrum of currently marketed antidepressant drugs. P7C3-A20 showed neuroprotective properties in rodent models of Parkinson’s disease, […]

Chelidonic acid monohydrate, a naturally occurring heterocyclic organic acid with a pyran skeleton, is isolated from Chelidonium majus and occurs naturally in plants of the Asparagales order. It has been found to regulate the closing of leaves of Cassia mimosoides at nightfall.

Fenoldopam hydrochloride (SKF-82526) is a synthetic benzazepine analog acting as a selective D1 receptor partial agonist. It was approved by the Food and Drug Administration (FDA) in September 1997 as an antihypertensive agent. Since fenoldopam is the only intravenous agent that improves renal perfusion, in theory it could be beneficial in hypertensive patients with concomitant […]

Cephalomannine (NSC-318735; taxol B) is a natural taxol analogue extracted from most Cephalotaxus species with antitumor activity.

Cyclopyrimorate is a novel and highly effective herbicide for weed control in rice fields. It acts by targeting homogentisate solanesyltransferase (HST) which is a downstream enzyme of 4-hydroxyphenylpyruvate dioxygenase in the plastoquinone (PQ) biosynthesis pathway.

U-99194 maleate is a novel and potent D3 antagonist

Chromocarb is a novel and potent bioactive compound

Sari 59-801 (Sari-59801; Sandoz 59-801) is a novel, oral and potent hypoglycemic agent that decreases blood glucose in several species. Also elevates plasma insulin in rats and mice.