TM-N1324 is a novel, orally bioavailable and potent GPR39 agonist agonist.

Diosmin (Barosmin) is a naturally occurring flavonoid glycoside isolated from various citrus fruits, hyssop, and rosemary, acting as an agonist of the aryl hydrocarbon receptor (AhR). ,

Betamethasone-17-butyrate-21-propionate is a topically used corticosteroid for treating inflammatory skin diseases.

Flurandrenolide (Fludroxycortide; Flurandrenolone) is a synthetic and topically administered glucocorticoid with anti-inflammatory and anti-allergic properties, used for treatment of skin irritations. Flurandrenolide exerts its effects by interacting with specific cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators […]

Medrogestone(also known as AY-62022) is a novel and potent progestin.

IDE1 (Inducer of definitive endoderm 1) is a novel, potent and cell-permeable inducer of definitive endoderm formation with EC50 of 125 nM). IDE1 induces Sox17 expression. It also activates TGF-β signaling and downstream Smad2 phosphorylation. IDE1 upregulates Nodal expression. It induces differentiation of mouse or human pluripotent stem cells (PSCs) by activating SMAD2 phosphorylation and […]

Triazavirin sodium (TZV, Riamilovir), a nucleoside analogue of nucleic acid, is a broad-spectrum and potent antiviral agent. It was originally developed as a potential treatment for pandemic influenza strains such as H5N1, and most of the testing that has been done has focused on its anti-influenza activity. However triazavirin has also been found to have […]

Sch-32615 (the S,S-diastereomer) is a novel and potent inhibitor of enkephalinase, an enzyme responsible for the degradation of endogenous enkephalins. The administration of SCH 32615 (3 mg/kg) decreased both D-1 and D-2 antagonist-induced catalepsy. In contrast, SCH 32615 (0.3 mg/kg) increased D-1 agonist-induced non-stereotyped grooming and D-2 agonist-induced stereotypies. SCH 32615 competitively antagonizes enkephalinase in […]

Triptorelin pamoate (AY25650; Wy42462; CL118532; AY-25650; Wy-42462; decapeptyl; trelstar), the pamoate salt of triptorelin, is a gonadotropin-releasing hormone agonist (GnRH agonist) used to treat advanced prostate cancer in men. It is also used as therapy in cases of gender dysphoria.

Vanin-1-IN-1 is a novel and potent inhibitor of vanin-1 enzyme, a cell surface associated, giycosyiphosphatidyS inositol (GPi) anchored protein which plays an important role in metabolism and inflammation.