Miconazole nitrate (R18134 nitrate) is an 14-α demethylase inhibitor and potential glucocorticoid receptor antagonist that inhibits ergosterol synthesis and fungal cell wall formation.

Penthiopyrad (MTF-753) is a novel and potent fungicide agent used in the protection of crops.

Anidulafungin (formerly also named as LY303366; Eraxis; Ecalta), a novel semisynthetic echinocandin derivative, which inhibits glucan synthase activity, used as an antifungal drug. Anidulafungin has been reported to inhibit systemic isolates of Candida species with the MIC90 values of 0.08μg/ml, 0.32μg/ml, 0.32μg/ml and 5.12μg/ml for C.albicans (n=99), C.glabrata(n=18), C.tropicalis(n=10), and C.parapsilosis (n=10), respectively. In addition, […]

Quercetin 7-rhamnoside is natural product of the flavonoid class.

Fenticonazole is an azole class of antifungal drug used locally as the nitrate form for the treatment of vulvovaginal candidiasis. It is a 14-α demethylase inhibitor and potentially a glucosamine-6-phosphate synthase inhibitor. It is active against a range of organisms including dermatophyte pathogens, Malassezia furfur, and Candida albicans. Application of fenticonazole nitrate 1 g intravaginal […]

Mefentrifluconazole (BAS 750F; trade name Revysol) is a novel potent azole derivative used as an agrochemical and broad-spectrum antifungal agent for controlling of diseases on cereals.

Luliconazole (also known as NND-502; NND502; Luzu) is an imidazole-based antifungal drug that is used for the topical treatment of interdigital tinea pedis. Luliconazole is a broad-spectrum antifungal agent that inhibits growth of all filamentous fungi except zygomycetes at low concentrations (MIC, ≦0.004–0.125 µg/ml), with dermatophytes being most susceptible (MIC, ≦0.004–0.008 µg/ml). As a 1% topical cream, […]

Amphotericin B (Fungizone; Amfocan; Ambisome; NSC527017; Amphozone; Fungilin; Amfocare; Amfotex; Amfotex) is a naturally occurring polyene antifungal agent approved for treating serious fungal infections and leishmaniasis, such as mucormycosis, coccidioidomycosis, candidiasis, aspergillosis, blastomycosis, and cryptococcosis.

Flusilazole (Olymp; DPX-6573; Sanction; Flusilazole; DPX6573; Flusilazol; DPX 6573; Nustar) is a potent organosilicon fungicide that has been used for the control of fungal infections on a variety of vegetable and fruit crops.

Dihydrochelerythrine is a bioactive natural product extracted from Corydalis yanhusuo and the leaves of Macleaya microcarpa with antifungal activity.