Amphotericin B

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
5g	$300	Check With Us
10g	$500	Check With Us
20g	$750	Check With Us

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Cat #: V6552 CAS #: 1397-89-3 Purity ≥ 99%

Description: Amphotericin B (Fungizone; Amfocan; Ambisome; NSC527017; Amphozone; Fungilin; Amfocare; Amfotex; Amfotex) is a naturally occurring polyene antifungal agent approved for treating serious fungal infections and leishmaniasis, such as mucormycosis, coccidioidomycosis, candidiasis, aspergillosis, blastomycosis, and cryptococcosis.

References: Sau K, et al. The antifungal drug amphotericin B promotes inflammatory cytokine release by a Toll-like receptor- and CD14-dependent mechanism. J Biol Chem. 2003 Sep 26;278(39):37561-8. Epub 2003 Jul 14.

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Molecular Weight (MW)	924.08
Molecular Formula	C47H73NO17
CAS No.	1397-89-3
Synonyms	Amphozone; Fungilin; Fungizone; AMPH-B; Fungizone; Liposomal Amphotericin B; NSC-527017; Amphotericin B; Amphotericine B; NSC 527017; Ambisome; NSC527017;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.0822 mL	5.4108 mL	10.8216 mL	21.6431 mL
5mM	0.2164 mL	1.0822 mL	2.1643 mL	4.3286 mL
10mM	0.1082 mL	0.5411 mL	1.0822 mL	2.1643 mL
20mM	0.0541 mL	0.2705 mL	0.5411 mL	1.0822 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.