Cariprazine (formerly known as MP-214 and RGH-188; Vraylar; Reagila) is a novel and potent antipsychotic drug that has been approved for the treatment of schizophrenia, as well as for bipolar disorder (manic/mixed and depressive episodes), and as an adjunctive agent for the treatment of major depressive disorders.
Nomifensine Maleate, the maleate salt of nomifensine, is a novel, potent and selective dopamine uptake inhibitor interacting with the dopamine transporter at a site different from that of cocaine; antidepressan.
Paliperidone palmitate (RO-92670; 9-Hydroxyrisperidone palmitate; RO92670) is a novel and potent dopamine antagonist and 5-HT2A antagonist that belongs to the atypical antipsychotic class of medications.
SKF 38393 HCl (SKF38393; SKF-38,393; SKF 38,393; SKF-38393A), the hydrochloride salt of SKF-38393, is a novel potent and selective dopamine D1 receptor agonist with IC50 of 110 nM, and the (+)-enantiomer is the active isomer.
PF-06256142 is a novel, potent and selective orthosteric agonist of the D1 receptor with D1 EC50 of 30 nM and D1 binding Ki of 12 nM.
Metoclopramide HCl (Maxolon, AHR3070-C, AHR 3070-C, Metozolv, Reglan), the hydrochloride salt of Metoclopramide, is a potent and selective dopamine D2 receptor antagonist used as a medication for treating stomach and esophageal problems such as nausea and vomiting.
(-)-Quinpirole HCl [(-)-LY 171555] is a highly potent psychoactive drug and research chemical which acts as a high affinity and selective D₂ and D₃ receptor agonist
BP 897 is a first potent and selective agonist of dopamine D3 receptor, and a weak antagonist of dopamine D2 receptor with Kis of 0.92 nM and 61 nM for D3 and D2 receptors.
GR-103691 is a novel,potent, selective dopamine D3 receptor antagonist .
SCH 23390 hydrochloride is a novel and potent dopamine receptor antagonist with Ki values of 0.2 and 0.3 nM for the D1 and D5.