SKF38393 HCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $300 | Check With Us |
| 1g | $515 | Check With Us |
| 5g | $1340 | Check With Us |
: Cat #: V1251 CAS #: 62717-42-4 Purity ≥ 98%
Description: SKF 38393 HCl (SKF38393; SKF-38,393; SKF 38,393; SKF-38393A), the hydrochloride salt of SKF-38393, is a novel potent and selective dopamine D1 receptor agonist with IC50 of 110 nM, and the (+)-enantiomer is the active isomer.
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| Molecular Weight (MW) | 291.77 |
|---|---|
| Molecular Formula | C16H17NO2 . HCl |
| CAS No. | 62717-42-4 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 58 mg/mL (198.8 mM)rr |
| Water: <1 mg/mLrr | |
| Ethanol: 6 mg/mL (20.6 mM) | |
| SMILES Code | OC1=C(O)C=C2C(C3=CC=CC=C3)CNCCC2=C1.[H]Cl |
| Synonyms | SKF-38393; SKF 38393A; SKF 38393; SKF38,393; SKF-38393 HCl; SKF-38393 hydrochloride; SKF38393; SKF-38,393; SKF 38,393; SKF-38393A; SKF38393A |
| Protocol | In Vitro | SKF-38393 hydrochloride induces a similar change in cytomorphology and increases the levels of media cAMP.SKF-38393 hydrochloride (10 μmol/L; 1 hour) induces increased threonine-phosphorylation of DA- and cAMP-regulated phosphoprotein of Mr 32 kD (DARPP-32) in cultured GC cells |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.4274 mL | 17.1368 mL | 34.2736 mL | 68.5471 mL |
| 5mM | 0.6855 mL | 3.4274 mL | 6.8547 mL | 13.7094 mL |
| 10mM | 0.3427 mL | 1.7137 mL | 3.4274 mL | 6.8547 mL |
| 20mM | 0.1714 mL | 0.8568 mL | 1.7137 mL | 3.4274 mL |
The molarity calculator equation
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The dilution calculator equation
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Step One: Enter information below
Dosage mg/kg
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Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
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mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.