Ropinirole HCl (formerly SKF 101468; SKF-101468A; SKF 101468A; Requip), the hydrochloride salt of ropinirole, is a potent and selective dopamine D2 receptors agonist ( Ki = 29 nM) of the non-ergoline class of medications used for PD-Parkinson’s disease, RLS/restless legs syndrome and extrapyramidal symptoms.

Lumateperone (ITI-722; ITI722; Caplyta) is a novel, potent, first-in-class and dual 5HT2A receptor antagonist and dopamine receptor phosphoprotein modulator (DPPM).

ABT-724 isa novel, potent and highly selective dopamine D4 receptor agonist with an EC50 of 12.4 nM.

Tavapadon (PF-6649751; CVL-751) is a partial dopamine receptor agonist with the potential to be used in the treatment of Parkinson’s disease and Alzheimer’s.

A-381393 is a novel and potent agonist of the dopamine D4 receptor.

Tetrahydroberberine is a natural isoquinoline alkaloid extracted from corydalis tuber with micromolar affinity for dopamine D(2) (pK(i) = 6.08) and 5-HT(1A) (pK(i) = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors (5-HT(1B), 5-HT(1D), 5-HT(3), and 5-HT(4); pK(i) < 5.00).

Tetracaine HCl (also called Amethocalne; Butylocaine; Curtacain; Decicain; Gingicain; PantocaineM; Intercaine; Leocaine; Menonasal; Niphanoid), the hydrochloride salt form of tetracaine, is a local anaesthetic and a channel function allosteric inhibitor.

Pergolide Mesylate (Permax; Pergotoliderived; LY127809; LY-127809), the mesylate salt of Pergolide, is a novel and potent antiparkinsonian agent which acts as a dopaminergic agonist.

PD 128907 HCl (PD-128907) is a novel, potent and selective dopamine D3 receptor agonist with EC50 of 0.64 nM, it exhibits 53-fold selectivity over dopamine D2 receptor.

Domperidone (R 33812; R-33812; KW5338; KW-5338; Motilium; Domperidona) is an orally bioactive dopamine D2 receptor antagonist and an antiemetic medication used to relieve nausea and vomiting.