Pramipexole 2HCl monohydrate (formerly known as SND 919; trade name Mirapex among others) is the dihydrochloride salt and hydrated form of of pramipexole which is a potent agonist of the Gαi-linked dopamine receptors D2, D3, and D4 with neuroprotective effects.
Chlorpromazine HCl (Promacid; Chloractil; Klorpromex; Fenactil; Largactil; Propaphenin; Sonazine; Thorazine), the Hydrochloride salt form of chlorpromazine, is a potent dopamine and potassium channel inhibitor used as an antipsychotic medication for the treatment of psychotic disorders such as schizophrenia.
Amisulpride (Solian; Amazeo; Amipride; Amival; Soltus; Aminosultopride; DAN-2163; DAN2163; Deniban; Amisulprida; Sulpitac; Sulprix) is a potent and atypical antipsychotic medication used to treat psychosis in schizophrenia and episodes of mania in bipolar disorders.
Penfluridol (formerly TLP-607; McN-JR-16341; R-16341; Acemap; Semap) is a 1st generation, long-acting and diphenylbutylpiperidine-based antipsychotic medication used for maintenance/long-term treatment of schizophrenia or other psychotic disorders.
Raclopride (formerly FLA 870) is a novel, potent and selective dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively.
Chlorprothixene (Paxyl; Rentovet; Truxal; Ro 4-0403; N-714; MK-184; Taractan; Tarasan), an typical antipsychotic drug of the thioxanthene class, is an antagonist of dopamine and histamine receptors with potential antipsychotic, sedative and antiemetic activity.
Raclopride (formerly also known as FLA 870) is a novel, potent and selective dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively.
ONC206 (ONC-206; ONC 206), an analogue of ONC201 (TRAIL inducer) and benzyl-flurobenzyl imipridone, is a novel, potent and selective antagonist of the D2-like dopamine receptors (DRD2/3/4) with a broad-spectrum of anticancer activity.
Metoclopramide HCl is a potent and selective dopamine D2 receptor antagonist. It is a medication used mostly for stomach and esophageal problems such as nausea and vomiting. It can help with emptying of the stomach in people with delayed stomach emptying due to either diabetes or following surgery, and help with gastroesophageal reflux disease. In […]
Tiapride HCl (Tiapridal), a benzamide derivative and an atypical neuroleptic agent, is a drug that selectively blocks D2 and D3 dopamine receptors in the brain.