Perphenazine (also known as Perphenazin, Trilafon, Etaperazine) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.
Fluphenazine HCl, the hydrochloride salt of Fluphenazine, is a novel and potent antipsychotic agent acting as a dopamine D2 receptor inhibitor.
Nomifensine is an isoquinoline analogue that prevents dopamine reuptake into synaptosomes.
Amisulpride HCl (Barhemsys; Solian; Amazeo; Aminosultopride; Amipride; Amival; Deniban; Amisulprida; Soltus; DAN-2163; Sulpitac; Sulprix), the hydrochloride salt of Amisulpride, is an atypical antipsychotic medication approved for treating psychosis in schizophrenia and episodes of mania in bipolar disorders.
Rotundine (also called L-THP or L-tetrahydropalmatine) is a naturally occuring alkaloid isolated from Corydalis rhizoma (a traditional Chinese medicinal plant) with analgesic activity.
Amantadine HCl (EXP-105-1; GP 38026; ADS5102; Influenol; Midantan; Midantane; Mydantane; NSC 83653; Symadine; Symmetrel; Trivaline; Virasol; Viregyt; Virofral; Virosol), the hydrochloride salt of amantadine, is an approved medication used to treat or prevent infections of the respiratory tract caused by a certain virus.
Chlorprothixene HCl is a typical antipsychotic drug of the thioxanthene class and an antagonist of dopamine and histamine receptors such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively.
Pramipexole (also known as SND 919), an agonist of the Gαi-linked dopamine receptors D2, D3, and D4, is a potent dopamine agonist of the non-ergoline class.
ABT-724 trihydrochloride is a novel, potent and highly selective dopamine D4 receptor agonist with an EC50 of 12.4 nM.
Sumanirole maleate (U-95666E; PNU-95666), the maleate salt of Sumanirole, is a first-in-class and highly selective D2 receptor full agonist (ED50 = ~46 nM) with antiparkinsonian effects.