Delamanid (formerly also known as OPC-67683; Deltyba) is a new neneration and potent drug that acts as a mycobacterial cell wall synthesis inhibitor for the treatment of multi-drug-resistant tuberculosis.

Besifloxacin HCl is a potent and fourth-generation fluoroquinolone antibiotic. Besifloxacin is a novel 8-chloro-fluoroquinolone agent with potent, bactericidal activity against prevalent and drug-resistant pathogens.besifloxacin is the most potent agent tested against gram-positive pathogens and anaerobes and is generally equivalent to comparator fluoroquinolones in activity against most gram-negative pathogens. Besifloxacin demonstrates potent, broad-spectrum activity, which is […]

Calicheamicin, formerly known as Calicheamicin gamma(1,I) or Calichemicin gamma1, is an potent enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora.

Ceftaroline fosamil (formerly also known as TAK-599 and PPI-0903) is a new generation of antibiotic belonging to the cephalosporin class with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).

Sancycline (formerly known as GS-2147) is a semi-synthetic tetracycline antibiotic that can be prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin.

DprE1-IN-1 (AZ-7371; TBA-7371), a 1,4-azaindole analog, is a potent and noncovalent inhibitor of decaprenylphosphoryl-β-d-ribose-2′-epimerase (DprE1) with a potential to become a drug candidate for treatment of tuberculosis. It inhibits DprE1 with ic50 of 10 nM; it also inhibits PDE6 with IC50 of 6 uM. It demonstrats efficacy in a rodent model of tuberculosis, making it […]

Moxifloxacin (Avelox, Avalox, Avelon, Vigamox, Moxeza; BAY12-8039; BAY12-8039; BAY 12-8039) is an orally bioactive, broad spectrum and 4th generation antibiotic agent of the fluoroquinolone class with high activity against both Gram positive and Gram negative bacteria.

BM-212 is a potent antimycobacterial agent and MmpL3 inhibitor.

Cefmetazole sodium (U-72791A sodium; CS-1170) is a potent 2nd-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity.

Chlortetracycline hydrochloride, formerly known as Aureomycin, is a potent and broad-spectrum antibiotic used as a veterinary medicine for pulmonary or digestive infections.