Moxalactam (also known as latamoxef, Lamoxactam, Festamoxin, LY-127935, 6059-S) is a new synthetic oxa-beta-lactam antibiotic administered intravenously or intramuscularly. It has a broad spectrum of activity against Gram-positive and Gram-negative aerobic and anaerobic bacteria, is particularly active against Enterobacteriaceae and is resistant to hydrolysis by beta-lactamases. Moxalactam has moderate activity against Pseudomonas aeruginosa, but on […]
Vancomycin HCl is the hydrochloride of vancomycin that is a narrow-spectrum glycopeptide antibacterial drug used to treat a number of bacterial infections. It is recommended intravenously as a treatment for complicated skin infections, bloodstream infections, endocarditis, bone and joint infections, and meningitis caused by methicillin-resistant Staphylococcus aureus. Blood levels may be measured to determine the […]
Cefditoren Pivoxil (also named ME-1207) is a broad-spectrum and 3rd-generation antibiotic against Gram-negative and Gram-positive bacteria. Cefditoren has MIC50/MIC90 results for Moraxella catarrhalis and Haemophilus influenzae of 0.12/0.5 and < or = 0.008/0.015 mg/mL, respectively. Cefditoren (MIC(90), 0.5 mg/mL) is 4- to 128-fold more active than comparison beta-lactams against the pneumoococci and was the most […]
Lactonic (di-acetylated) Sophorolipid is a naturally occurring glycolipid generated from fermentation of sugar by yeasts including C. bombicola.
AU1235 is an inhibitor of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane that targets MmpL3.
Sulbactam (CP 45899 and Betamaze) is a potent and irreversible β-lactamase inhibitor given in combination with β-lactam antibiotics to inhibit β-lactamase, an enzyme produced by bacteria that destroys antibiotic activity.
Biapenem (also called L-627, CLI 86815, LJC10627) is a potent carbapenem antibiotic with activity against both Gram-positive and Gram-negative bacterial strains. Biapenem has activity comparable to those of Imipenem and Meropenem against all groups of anaerobes with MICs for 90% of the strains tested of 0.06 to 2 mg/mL. Biapenem is more active than ampicillin-sulbactam, […]
Desacetylcefotaxime formerly known as 3-Desacetyl cefotaxime, is an impurity of cefotaxime sodium salt (sc-202989), a broad-spectrum cephalosporin antibiotic.
Dimethyl sulfoxide (also known as DMSO or Methyl Sulfoxide) is an aprotic solvent that dissolves both polar and nonpolar compounds.
Meropenem (formerly known as SM-7338; SM7338; ICI194660; Vabomere; Merrem), a beta-lactam of the carbapenem class, is an ultra-broad-spectrum injectable β-lactam antibiotic used to treat a wide variety of infections. Meropenem has been shown to inhibit penicillinase-negative, -positive and methicillin-susceptible staphylococci. Meropenem has an antibacterial spectrum which is broadly similar to that of imipenem but, whilst […]