Sancycline

This product is for research use only, not for human use. We do not sell to patients.

Sancycline
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$450Check With Us
500mg$750Check With Us
1g$1125Check With Us

Cat #: V4105 CAS #: 808-26-4 Purity ≥ 98%

Description: Sancycline (formerly known as GS-2147) is a semi-synthetic tetracycline antibiotic that can be prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of declomycin.

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Molecular Weight (MW)414.41
Molecular FormulaC21H22N2O7
CAS No.808-26-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: ≥ 80 mg/mLr
Water: < 1mg/mLr
Ethanol: N/A
SMILES CodeO=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N
SynonymsGS 2147; GS-2147; GS2147; Sancycline; 6-Demethyl-6-deoxytetracycline; Bonomycin; NSC 51812; Sanciclina.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.4131 mL12.0653 mL24.1307 mL48.2614 mL
5mM0.4826 mL2.4131 mL4.8261 mL9.6523 mL
10mM0.2413 mL1.2065 mL2.4131 mL4.8261 mL
20mM0.1207 mL0.6033 mL1.2065 mL2.4131 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.