Amoxicillin (Amoxycillin and amox), a moderate-spectrum, bacteriolytic, orally bioactive β-lactam antibiotic of the penicillin class, is widely used to treat a number of bacterial infections, including bronchitis, pneumonia, and infections of the ear, nose, throat, skin, and urinary tract.

Danofloxacin (formerly CP-76136-27; CP76136-27) is a fluoroquinolone antibiotic used in veterinary medicine.

Eravacycline 2HCl (formerly TP-434 or 7-fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline; trade name: Xerava), the dihydrochloride salt of eravacycline, is an approved antibiotic of the tetracycline class.

Iclaprim (formerly known as AR-100 and RO-482622) is a novel diaminopyrimidine, and a selective inhibitor of dihydrofolate reductase which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 μg/mL. It has shown potent, extended-spectrum in vitro activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, vancomycin-intermediate and vancomycin-resistant S. aureus and macrolide-, […]

Thiolutin (formerly Acetopyrrothin and NSC-3927), is a potent and naturally occusinrg disulfide-containing antibiotic and anti-angiogenic agent isolated from Streptomyces, it acts as a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases, also inhibits the JAMM metalloproteases Csn5, Associated-molecule-with-the-SH3-Domain-of-STAM (AMSH) and Brcc36.

Sitafloxacin 1.5Hydrate (DU-6859a), a new-generation, broad-spectrum and oral fluoroquinolone class of antibiotic, is highly active against many Gram-positive, Gram-negative and anaerobic clinical isolates, including strains resistant to other fluoroquinolones, was recently approved in Japan for the treatment of respiratory and urinary tract infections. In terms of clinical efficacy, oral sitafloxacin was noninferior to oral levofloxacin […]

Tazobactam (formerly CL298741; YTR830H; Zerbaxa) is a β-lactamase inhibitor approved for us in combination other antibiotics such as Ceftolozane (Zerbaxa) for the treatment of bacterial infections. Tazobactam is also combined with the extended spectrum β-lactam antibiotic piperacillin in the drug piperacillin/tazobactam, one of the preferred antibiotic treatments for nosocomial pneumonia caused by Pseudomonas aeruginosa.

Tetracycline (NSC-108579, Sumycin among others) is a potent and broad-spectrum antibiotic used to treat a number of infections such as gram-positive and gram-negative bacteria.

Sibofimloc, formerly known as VRT-1353385 and Antibiotic-202, is an Escherichia coli fimbrial (FimH) adhesin inhibitor.

Amoxicillin Sodium (Amoxycillin), a potent, moderate-spectrum, bacteriolytic, orally bioactive β-lactam antibiotic of the penicillin class, is widely used to treat various bacterial infections, including bronchitis, pneumonia, and infections of the ear, nose, throat, skin, and urinary tract. Though it can be highly effective in treating bacterial infections, it also comes with a list of potential […]