Azathramycin (also known as Azaerythromycin A and Desmethyl Azithromycin) is a novel and potent macrolide antibiotic that contains a cladinose.

DIMBOA, is a novel and potent antibiotic and benzoxazinoid, it is a part of the chemical defense system of graminaceous plants .

Cefaclor (trade name: Ceclor; Biocef, Medacef, Distaclor, Keflor, Raniclor among others) is a potent, second-generation cephalosporin / beta-lactam antibiotic approved for use in the treatment of certain bacterial infections such as pneumonia and infections of the ear, skin, throat, lung, and urinary tract.

Pidotimod (PGT-1A) is an oral immunomodulator/immunostimulant and a synthetic dipeptide with immunomodulatory properties against adaptive and the innate immune systems.

Cephalosporin C zinc salt, zinc salt is the salt form of cephalosporin C, is a novel and potent inhibitor of SAMHD1 with antibiotic effects.

Olanexidine HCl (also known as OPB-2045 HCl) is a novel monobiguanide analog with bactericidal activity.

Penicillin G procaine (PGP) is a potent and semisynthetic antibiotic drug composed of penicillin G with Procaine.

Usaramine is natural product of the pyrrolizidine alkaloid class, and is isolated from seeds of Crolatalaria pallida.

Avibactam (NXL104; NXL-104; Avycaz) is a novel, covalent but reversible inhibitor of β-lactamase belonging to the the non-β-lactam antibiotic, inhibiting β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively.

BTZ043, also known as 8-Nitro-benzothiazinones (BTZs), is a potent inhibitor of decaprenyl-phosphoribose-epimerase (DprE1) with MIC values of of 2.3 nM and 9.2 nM for M. tuberculosis H37Rv and Mycobacterium smegmatis, respectively. It has potential to be used as a antimycobacterial agent that kill Mycobacterium tuberculosis by blocking arabinan synthesis. The inhibition of BTZ-resistant DprE1 followed […]