Cephalosporin C zinc salt
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 2g | $300 | Check With Us |
| 5g | $550 | Check With Us |
| 10g | $825 | Check With Us |
: Cat #: V30010 CAS #: 59143-60-1 Purity ≥ 99%
Description: Cephalosporin C zinc salt, zinc salt is the salt form of cephalosporin C, is a novel and potent inhibitor of SAMHD1 with antibiotic effects.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 478.78 |
|---|---|
| Molecular Formula | C16H19N3O8SZn |
| CAS No. | 59143-60-1 |
| SMILES Code | O=C(C(N12)=C(COC(C)=O)CS[C@]2([H])[C@H](NC(CCC[C@@H](N)C([O-])=O)=O)C1=O)[O-].[Zn+2] |
| Synonyms | Cephalosporin C Zinc Salt |
| Protocol | In Vitro | Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 ± 0.1 μM, 200-fold more potent than Na+ salt form of Cephalosporin C (ICC50CC-Na = 213 ± 30 μM). |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.0886 mL | 10.4432 mL | 20.8864 mL | 41.7728 mL |
| 5mM | 0.4177 mL | 2.0886 mL | 4.1773 mL | 8.3546 mL |
| 10mM | 0.2089 mL | 1.0443 mL | 2.0886 mL | 4.1773 mL |
| 20mM | 0.1044 mL | 0.5222 mL | 1.0443 mL | 2.0886 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.