N-Acetyl-d-mannosamine (also known as N-Acetyl-D-mannosamine; ManNAc; DEX M-74) is a compound that has the potential for the treatment of neural disorders such as hereditary inclusion body myopathyan.

Cinoxacin (Cinobac; Compound 64716) was a synthetic antimicrobial agent for oral administration.

Avibactam sodium hydrate (NXL104; NXL-104 hydrate; Avycaz), the sodium salt and hydrated form of avibactam, is a novel, potent, and covalent reversible non-β-lactam β-lactamase inhibitor with antibiotic activity.

Physcion (also known as Physcione) is a naturally occuring anthraquinone isolated from roots of Rheum officinale Baill. Physcion has been commercialised in China for controlling powdery mildews. Physcion controls powdery mildew mainly through changing the expression of defence-related genes, and especially enhancing expression of leaf-specific thionin in barley leaves. Rhein induces apoptosis in cancer cell […]

Midecamycin, a novel and potent acetoxy-substituted macrolide antibiotic, is a naturally occurring 16-membered macrolide that belongs to the acetoxy-substituted macrolide antibiotics.

BTZ043 racemate, the racemic mixture (R- and S-isomer) of BTZ043, is a decaprenylphosphoryl-β-D-ribose 2′-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis. BTZ043 displayed similar activity against all clinical isolates of M. tuberculosis that were tested, including extensively drug-resistant and multidrug-resistant strains, indicating that it targets a previously unknown biological function. […]

Mupirocin (BRL-4910A; Pseudomonic acid) is an potent isoleucyl t-RNA synthetase inhibitor and an orally bioactive antibiotic isolated from Pseudomonas fluorescens.

Cefdinir (also known as FK 482, PD 134393, CI-983) is a potent, orally bioavailable, semi-synthetic, and broad-spectrum cephalosporin class of antibiotic used to treat bacterial infections in many different parts of the body including the ear, sinus, throat, and skin. . Cefdinir, a new oral 2-amino-5-thiazolyl cephalosporin, inhibits the luminol-amplified chemiluminescence (LACL) response of human […]

LED209 is a novel non-toxic inhibitor of the binding signals to QseC, preventing its autophosphorylation and consequently inhibiting QseC-mediated activation of virulence gene expression.

Norvancomycin (NVCM; A-51568A; N-Demethylvancomycin) hydrochloride is a macrocyclic antibiotic of the glycopeptide class that is widely used in the treatment of endocarditis, osteomyelitis, pneumonia, sepsis or soft tissue infections caused by Staphylococcus (including Methicillin-resistant strains and multidrug-resistant microbial strains).