TBAJ-587, a diarylquinoline analog, is a novel and potent anti-tuberculosis agent which inhibits M.tb strain H37Rv growth with MIC90s of 0.006 and<0.02 µg/mL in MABA and LORA assay, respectively.

Licoflavonol is a novel and potent inhibitor of the type three secretion system of Salmonella enterica serovar Typhimurium.

Geneticin G418 (G-418 disulfate) is a potent aminoglycoside antibiotic of the gentamicin B1 class, blocking polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.

GSK656 (GSK-3036656 and GSK-070) is a novel and potent antitubercular agent which acts as an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS), with an IC50 of 0.2 μM. There is an urgent need to develop new and safer antitubercular agents that possess a novel mode of action. GSK3036656 (abbreviated as GSK656) shows potent inhibition […]

Pinocembrin [(+)-Pinocoembrin; Dihydrochrysin; Galangin flavanone] is a naturally occuring flavonoid widely found in damiana, honey, fingerroot, and propolis with potent antioxidant, antimicrobial, anti-inflammatory and gastrointestinal protective effects.

AFN-1252 (AFN-12520000; API-1252; Debio-1452) is a novel and potent inhibitor of enoyl-(acyl-carrier protein) reductase Fabl with the potential for the treatment of acute bacterial skin.

Cloxacillin Sodium hydrate (HSDB-3042), a semi-synthetic and chlorinated derivative of Oxacillin, is a potent and orally bioactive antibacterial agent acting as a β-lactamase inhibitor with an IC50 of 0.04 µM.

Polymyxin B nonapeptide is a potent and natural cyclic peptide obtained from Polymyxin B by proteolytic removal of its terminal amino acyl residue.

Tobramycin Sulfate (Tobraneg; Dartobcin; Deoxykanamycin B; Nebcine; Tobrasix), the sulfate salt of Tobramycin, is a potent, broad-spectrum and aminoglycoside antibiotic that binds to 70S ribosomal subunit, inhibits translocation and elicits miscoding.

Amoxicillin Trihydrate (Amoxycillin), a potent, broad-spectrum, bacteriolytic, orally bioactive β-lactam antibiotic of the penicillin class, is widely used to treat various bacterial infections, including bronchitis, pneumonia, and infections of the ear, nose, throat, skin, and urinary tract.