MK-3903 (MK3903) is a novel, potent and selective AMPK (AMP-activated protein kinase) activator with EC50 of 8 nM for α1 β1 γ1 subunit, leading to improved lipid metabolism and insulin sensitization in mice.

Nilotinib HCl hydrate (formerly also known as AMN-107, AMN107 HCl hydrate) is a potent, orally bioavailable aminopyrimidine-derivative Bcr-Abl inhibitor with IC50 less than 30 nM in Murine myeloid progenitor cells.

A-769662 (A769662; A 769662), a thienopyridone analog, is a potent, alloesteric and reversible activator of AMPK (AMP-activated protein kinase) with antidiabetic activity.

EX229 (EX-229; AMPK Activator 991), a benzimidazole analog, is a novel, potent and allosteric AMPK (AMP-activated protein kinase) activator with Kd values of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1 and α1β2γ1 in biolayer interferometry, respectively.

Dorsomorphin (BML-275) is a reversible and selective AMPK (AMP-activated protein kinase) inhibitor with a Ki of 109 nM in cell-free assays, exhibiting little effects against closely related kinases such as ZAPK, SYK, PKCθ, PKA, and JAK3.

TMPA is an antagonist of nuclear receptor Nur77 and LKB1 interaction.

PF-06409577 (PF06409577) is a potent, selective, orally bioavailable, allosteric activator of AMPK α1β1γ1 (5′ adenosine monophosphate-activated protein kinase) with the potential to be used for diabetic nephropathy.

6-Gingerol is a novel and potent active constituent of fresh ginger.

WZ4003 is a novel, potent and highly specific inhibitor of NUAK kinases.

GSK621 is a novel, potent and selective activator of AMP-activated protein kinase (AMPK) with potential antitumor activity.