TMPA

This product is for research use only, not for human use. We do not sell to patients.

TMPA
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$1350Check With Us
250mg$2250Check With Us
500mg$3375Check With Us

Cat #: V33400 CAS #: 1258275-73-8 Purity ≥ 99%

Description: TMPA is an antagonist of nuclear receptor Nur77 and LKB1 interaction.

References: Zhan YY, et al. The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK. Nat Chem Biol. 2012 Nov;8(11):897-904.

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Product Promise

Promise
Molecular Weight (MW)380.48
Molecular FormulaC21H32O6
CAS No.1258275-73-8
SMILES CodeCOC1=C(CC(OCC)=O)C(C(CCCCCCC)=O)=CC(OC)=C1OC
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.6283 mL13.1413 mL26.2826 mL52.5652 mL
5mM0.5257 mL2.6283 mL5.2565 mL10.5130 mL
10mM0.2628 mL1.3141 mL2.6283 mL5.2565 mL
20mM0.1314 mL0.6571 mL1.3141 mL2.6283 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.