PF-06409577
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1250 | Check With Us |
| 500mg | $1850 | Check With Us |
| 1g | $2775 | Check With Us |
: Cat #: V3110 CAS #: 1467057-23-3 Purity ≥ 98%
Description: PF-06409577 (PF06409577) is a potent, selective, orally bioavailable, allosteric activator of AMPK α1β1γ1 (5′ adenosine monophosphate-activated protein kinase) with the potential to be used for diabetic nephropathy.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 341.79 |
|---|---|
| Molecular Formula | C19H16ClNO3 |
| CAS No. | 1467057-23-3 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: ~68 mg/mL (199 mM)r |
| Water: <1 mg/mLr | |
| Ethanol: ~68 mg/mL (199 mM) | |
| SMILES Code | O=C(C1=CNC2=C1C=C(C3=CC=C(C4(O)CCC4)C=C3)C(Cl)=C2)O |
| Synonyms | PF-06409577; PF-6409577; PF 06409577; PF6409577; PF06409577; PF 6409577 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.9258 mL | 14.6289 mL | 29.2577 mL | 58.5155 mL |
| 5mM | 0.5852 mL | 2.9258 mL | 5.8515 mL | 11.7031 mL |
| 10mM | 0.2926 mL | 1.4629 mL | 2.9258 mL | 5.8515 mL |
| 20mM | 0.1463 mL | 0.7314 mL | 1.4629 mL | 2.9258 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.