RSL3
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $700 | In Stock |
| 250mg | $1250 | In Stock |
| 500mg | $1875 | In Stock |
: Cat #: V14062 CAS #: 1219810-16-8 Purity ≥ 98%
Description: RSL3 is a novel and potent inhibitor of glutathione peroxidase 4 (GPX4), which is able to reduce the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 440.88 |
|---|---|
| Molecular Formula | C23H21ClN2O5 |
| CAS No. | 1219810-16-8 |
| SMILES Code | O=C(OC)[C@@H]1N(C(CCl)=O)[C@@H](C2=CC=C(C(OC)=O)C=C2)C3=C(C(C=CC=C4)=C4N3)C1<br/> |
| Synonyms | RSL3; RSL-3; RSL 3 |
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.2682 mL | 11.3410 mL | 22.6819 mL | 45.3638 mL |
| 5mM | 0.4536 mL | 2.2682 mL | 4.5364 mL | 9.0728 mL |
| 10mM | 0.2268 mL | 1.1341 mL | 2.2682 mL | 4.5364 mL |
| 20mM | 0.1134 mL | 0.5670 mL | 1.1341 mL | 2.2682 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.