Verdiperstat (also known as AZD3241) is a novel, potent, selective, irreversible and orally bioactive myeloperoxidase/MPO inhibitor (IC50 = 630 nM) with the potential to be used in the treatment of neurodegenerative brain disorders.

ML-210 (ML210; CID49766530) is a novel, potent, selective RAS inhibitor, and also a covalent inhibitor of glutathione peroxidase 4 (GPX4) with anticancer activity.

RSL3 is a novel and potent inhibitor of glutathione peroxidase 4 (GPX4), which is able to reduce the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell.