CX-6258 HCl hydrate is a novel, potent, selective and orally bioactive pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3, respectively.

TCS-PIM-1-4a ( (the mixture of E- and Z-enantiomers of SMI-4a) is a novel Pim inhibitor with IC50 of 13 nM for Pim-1 and 2.3 μM for Pim-2.

Pim1/AKK1-IN-1 is a potent multi-kinase inhibitor, targeting Pim1, AKK1, MST2, LKB1, MPSK1, and TNIK.

TCS PIM-1 1, also known as sc-204330, is a highly potent substituted pyridone and selective ATP-competitive inhibitor of Pim-1 kinase with IC50 of 50 nM, it displays good selectivity over Pim-2 and MEK1/MEK2(IC50s >20,000 nM).

SGI-1776 is a novel, potent and ATP-competitive pan-inhibitor of the serine/threonine family of Pim kinase (an enzyme regulating cell survival) with potential antitumor activity.

PIM447 (also known as LGH447) is a novel and potent pan-PIM (proviral insertion site of Moloney murine leukemia) kinase inhibitor with Ki values of 6 pM, 18 pM, 9 pM for PIM1, PIM2, PIM3 respectively.

AZD1208 is a novel, highly selective, ATP-competitive and orally bioavailable small molecule pan-inhibitor of Pim kinase with potential antitumor activity.

CX-6258 is a novel, potent, selective and orally bioactive pan-Pim kinase inhibitor with IC50 of 5 nM, 25 nM and 16 nM for Pim1, Pim2, and Pim3, respectively.

CX-6258 HCl(known also as CX-6258 hydrochloride) is a novel, highly potent and orally bioactive pan-Pim kinase inhibitor with potential anticancer activity.

(Z)-SMI-4a (the Z-enantiomer of SMI-4a), a novel benzylidene-thiazolidine-2, 4-dione small molecule, is a potent and selective Pim1 inhibitor with potential antineoplastic activity.