TS-011 (TS 011; TS011) is a novel and potent inhibitor of 20-Hydroxyeicosatetraenoic acid synthesis. It can improve cerebral microcirculatory autoregulation impaired by middle cerebral artery occlusion in mice.

Silychristin is a flavonoid rich in milk thistle fruit that has antioxidant effects. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8 and can strongly inhibit T3 uptake with IC50 of 110 nM.

Isoguanine is a purine base, an enantiomer of guanine. building block/intermediates of organic synthesis.

Britannin is a naturally occurring sesquiterpene lactone found in Inula caspica and Asteraceae family of plants with antiproliferative activity on the MCF-7 and MDA-MB-468 human breast cancer cells. Britannin inhibits growth of MCF-7 and MDA-MB-468 breast cancer cells through the activation of the mitochondrial apoptotic pathway and may potentially serve as an agent for breast […]

Substance P (Neurokinin P) is a neuropeptide that works as a neurotransmitter and neuromodulator in the central nervous system. The endogenous receptor of Substance P is neurokinin 1 receptor (NK1R).

5-HT7 agonist 1 is a selective 5-HT7 receptor agonist (activator) with IC50 of 222.93 nM and may be utilized to study diseases related to 5-HT7 receptors, like central nervous system diseases.

Recilisib (ON-01210; ON 01210; ON01210; EX-RAD) is a novel and potent radioprotectant that Onconova Therapeutics is testing in phase I clinical trials to treat acute radiation syndrome. Through the activation of the AKT pathway, it lessens radiation damage.

ATP disodium salt hydrate (Adenosine 5′-triphosphate disodium salt hydrate) is an important substance for energy storage and metabolism in the body, providing energy for metabolism and functioning as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation.

PLGA (50:50) (poly(lactic-co-glycolic acid) (50:50)) is a copolymer of polylactic acid (PLA) and polyglycolic acid (PGA) that can be manufactured for drug delivery and tissue engineering applications installation.

Cirsiliol is a potent and specific 5-lipoxygenase inhibitor and a competitive low-affinity benzodiazepine receptor ligand.