Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extracellular domain of human CTLA4 and fragments of the Fc portion of human IgG1 (hinge, CH2 and 3 domains). Abatacept is a selective T-cell costimulation modulator and a protein-active molecule used in autoimmune diseases.
DZ2002 is an orally bioactive, reversible, low cytotoxic type III SAHH inhibitor (Ki=17.9 nM) with good immunosuppressive activity. DZ2002 prevents the development of experimental skin fibrosis by reversing the profibrotic phenotype of a variety of cell types. DZ2002 may be utilized in the research/study of autoimmune diseases like lupus syndrome and systemic sclerosis.
DZ2002 is an orally bioactive, reversible, low cytotoxic type III SAHH inhibitor (Ki=17.9 nM) with good immunosuppressive activity. DZ2002 prevents the development of experimental skin fibrosis by reversing the profibrotic phenotype of a variety of cell types. DZ2002 may be utilized in the research/study of autoimmune diseases like lupus syndrome and systemic sclerosis.
I2906 has activity against Mycobacterium tuberculosis (TB).
I2906 has activity against Mycobacterium tuberculosis (TB).
Araloside VII (Congmunoside VII) is a saponin compound found in Aralias elate.
(20S)-Protopanaxatriol is a metabolite of ginsenosides and acts by binding to glucocorticoid receptor and estrogen receptor (Estrogen Receptor/ERR). (20S)-Protopanaxatriol is also an inhibitor (blocker/antagonist) of LXRα. (20S)-Protopanaxatriol has broad anti-cancer effect.
1-BCP (Piperonylic acid piperidide) is a centrally active molecule that regulates the gated current of AMPA receptors. 1-BCP is a bioactive molecule that enhances memory.
(±)-Medicarpin is a naturally occuring pterocarpan and also an isoflavonoid that has been extracted from several medicinal plant species with various biological effects, including Sophora japonica as a phytoalexin, Zollernia paraensis and Platymiscium yucatamun with antifungal properties, Machaerium aristulatum, Platymiscium floribundum, and Brazilian red propolis with cytotoxic effects, and Dalbergia oliveri as a larvicidal compound. […]
Ornipressin is a potent vasoconstrictor, hemostatic and renally active molecule.