Silychristin

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
1mg	$110	To Be Confirmed
5mg	$210	To Be Confirmed

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Cat #: V30854 CAS #: 33889-69-9 Purity ≥ 99%

Description: Silychristin is a flavonoid rich in milk thistle fruit that has antioxidant effects. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8 and can strongly inhibit T3 uptake with IC50 of 110 nM.

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Molecular Weight (MW)	482.4362
Molecular Formula	C25H22O10
CAS No.	33889-69-9
Storage	Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.0728 mL	10.3641 mL	20.7281 mL	41.4563 mL
5mM	0.4146 mL	2.0728 mL	4.1456 mL	8.2913 mL
10mM	0.2073 mL	1.0364 mL	2.0728 mL	4.1456 mL
20mM	0.1036 mL	0.5182 mL	1.0364 mL	2.0728 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.