BDC2.5 mimotope 1040-31, BDC2.5 TCR active peptide, is a strong agonist peptide for diabetic T cell clone BDC2.5. 1040-31 is specific for BDC2.5 TCR Tg+ T cells.
Fmoc-PEA (Example 1-2) can be used as a cleavable (degradable) cross-linker for Antibody-drug conjugates (ADC).
Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide 2HCl) is a major metabolite of Quetiapinem, which is a 2nd-generation antipsychotic acting as a 5-HT receptor agonist and a dopamine receptor antagonist.
Withanolide A is found in the Indian herb Ashwagandha. It can regenerate neuronal processes and rebuild synapses in severely damaged neurons.
Peptide 401 is a potent mast cell degranulation peptide developed from bee venom that can inhibit vascular permeability.
Col003 is a potent and selective inhibitor of Hsp47 that competitively binds to the collagen-binding site of Hsp47 (IC50, 1.8 μM). Col003 inhibits the interaction between Hsp47 and collagen and inhibits collagen secretion by destroying the stability of the collagen triple helix. Col003 may be utilized in related research on pulmonary fibrosis.
NO-prednisolone is a Prednisolone analogue that releases nitric oxide (NO). NO-prednisolone effectively stimulates IL-10 production in the body.
FAAH inhibitor 1 (Benzothiazole analog 3) is a fatty acid amide hydrolase (FAAH) inhibitor (antagonist) with IC50 of 18 nM.
Edpetiline is a major alkaloid from P. eduardi. Edpetiline has significant anti~inflammatory effects.
5-Iodo-indirubin-3′-monoxime is a potent inhibitor of GSK-3β, CDK5/P25 and CDK1/cyclin B. It competes with ATP to bind to the catalytic site of the enzyme, with IC50s of 9, 20 and 20 respectively. 25 nM.