5-Iodo-indirubin-3′-monoxime is a potent inhibitor of GSK-3β, CDK5/P25 and CDK1/cyclin B. It competes with ATP to bind to the catalytic site of the enzyme, with IC50s of 9, 20 and 20 respectively. 25 nM.

Caffeic acid is an inhibitor (blocker/antagonist) of TRPV1 ion channel and 5-lipoxygenase (5-LO).

Caffeic acid is an inhibitor (blocker/antagonist) of TRPV1 ion channel and 5-lipoxygenase (5-LO).

(Z)-Thiothixene is an antagonist of serotonergic receptor, disclosed in patent US 20150141345 A1.

(Z)-Thiothixene is an antagonist of serotonergic receptor, disclosed in patent US 20150141345 A1.

AGX51 is the first pan-Id (inhibitors of DNA-binding/differentiation proteins) antagonist and degrader. AGX51 inhibits the Id1-E47 interaction, leading to ubiquitin-mediated degradation of Ids, cell growth arrest and reduced viability. AGX51 can inhibit TNBC with IC50 of about 25 nM. AGX51 may be utilized in cancer-related research.

AGX51 is the first pan-Id (inhibitors of DNA-binding/differentiation proteins) antagonist and degrader. AGX51 inhibits the Id1-E47 interaction, leading to ubiquitin-mediated degradation of Ids, cell growth arrest and reduced viability. AGX51 can inhibit TNBC with IC50 of about 25 nM. AGX51 may be utilized in cancer-related research.

Aloe-emodin-8-O-β-D-glucopyranoside is a compound extracted from Saussrurea lappa and is a mild inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with IC50 of 26.6 μM.

Aloe-emodin-8-O-β-D-glucopyranoside is a compound extracted from Saussrurea lappa and is a mild inhibitor of human protein tyrosine phosphatase 1B (hPTP1B) with IC50 of 26.6 μM.

TC HSD 21 is a potent inhibitor of 17β-hydroxysteroid dehydrogenase type 3 (17β-HSD3) with IC50 of 14 nM. TC HSD 21 has good selectivity for 17β-HSD isoenzymes and nuclear receptors. .