Naltrexone HCl is a potent opioid receptor antagonist used mainly in the management of alcohol dependence and opioid dependence.

Naloxegol Oxalate (AZ13337019; AZ-13337019; NKTR118; NKTR-118; Movantik; PEGylated naloxol; Moventig), the Oxalate salt of naloxegol which is the pegylated analog of α-naloxol, is a peripherally-acting and selective μ-opioid antagonist with anti-constipation effects.

Naloxone HCl is an inverse opioid agonist drug used to counteract the effects of opiate overdose.

Trimebutine Maleate (also known as Mebutin) is a potent agonist of peripheral mu, kappa and delta opiate receptors, it is used as spasmolytic agent for treatment of both acute and chronic abdominal pain.