Naloxegol Oxalate

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
500mg	$850	Check With Us
1g	$1450	Check With Us
5g	$4350	Check With Us

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Cat #: V9135 CAS #: 1354744-91-4 Purity ≥ 98%

Description: Naloxegol Oxalate (AZ13337019; AZ-13337019; NKTR118; NKTR-118; Movantik; PEGylated naloxol; Moventig), the Oxalate salt of naloxegol which is the pegylated analog of α-naloxol, is a peripherally-acting and selective μ-opioid antagonist with anti-constipation effects.

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Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	741.828
Molecular Formula	C36H55NO15
CAS No.	1354744-91-4

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.3480 mL	6.7401 mL	13.4802 mL	26.9604 mL
5mM	0.2696 mL	1.3480 mL	2.6960 mL	5.3921 mL
10mM	0.1348 mL	0.6740 mL	1.3480 mL	2.6960 mL
20mM	0.0674 mL	0.3370 mL	0.6740 mL	1.3480 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.