LY-2940094 is a nociceptin receptor antagonist potentially for the treatment of major depressive disorder and alcoholism.

LY-2940094 is a novel, potent, selective and orally bioavailable nociceptin receptor (NOP receptor) antagonist that can be potentially used for the treatment of major depressive disorder and alcoholism.

SNC80 (SNC-80; SNC 80) is a novel, potent, selective, systemically active non-peptide δ(delta)-opioid agonist with potential antinociceptiveand pro-convulsant activities in vivo.

(R)-(-)-GR103545 fumarate is the active enantiomer (R-isomer) of GR89696, which is a selective kappa opioid receptor agonist.

Alvimopan (also known as ADL 8-2698; LY 246736; HSDB-7704) is a novel peripheral micro opioid antagonist in clinical development for the management of post-operative ileus and opioid-induced bowel dysfunction.

Cebranopadol 1α,4α-stereoisomer is a stereoisomer of cebranopadol.

Alvimopan (also known as ADL 8-2698; LY 246736; HSDB-7704) is a novel peripheral micro opioid antagonist in clinical development for the management of post-operative ileus and opioid-induced bowel dysfunction.

Matrine (Vegard; α-Matrine; Matridin-15-one; NSC-146051; NSC146051; (+)-Matrine) is a naturally occuring alkaloid found in plants from the Sophora family.

CYM51010 (also known as ML335; CYM-51010; CID23723457), is a biased ligand of μ-opioid receptor – δ-opioid receptor heterodimers (EC50=403 nM), exhibiting anti-nociceptive activity similar to morphine but with a decreased levels of tolerance development and withdrawal symptoms.

Asimadoline is a bioactive compound.