Citreoviridin (BRN-5311865; BRN5311865) is a novel and potent toxin/mycotoxin isolated from several Penicillium citreoviride NRRL 2579. It can inhibit the mitochondrial ATP synthetase system. Citreoviridin inhibits cell proliferation and enhances apoptosis of human umbilical vein endothelial cells.
Ikarisoside F is a novel and potent flavonol glycoside
3,4-Dimethoxyphenol is a novel and potent phenylpropanoid compound
BCN-exo-PEG3-NH2 is a novel and potent PROTAC linker
(R)-Verapamil HCl, the hydrochloride salt of Verapamil R-isomer, is a novel and potent P-Glycoprotein (MRP1, efflux pump in multidrug resistant tumor cells) inhibitor. It blocks MRP1 mediated transport, leading to chemosensitization of MRP1-overexpressing cells to anticancer drugs.
Syncytial Virus Inhibitor-1 is a novel and potent respiratory syncytial virus (RSV) inhibitor which is orally bioavailable. It inhibits the fusion of respiratory syncytial virus (RSV) with EC50s of 0.002 μM, 0.004 μM, and 0.002 μM for RSV Long, RSV A2, and RSV B strains, respectively.
Pivagabine is a novel and potent hydrophobic 4-aminobutyric acid
Nilotinib D6 is the hexa-deuterated form of Nilotinib (AMN-107; AMN107; Tasigna), which is an FDA-approved drug for the treatment of imatinib-resistant chronic myelogenous leukemia.
Bis-Mal-PEG11 is a novel and potent PROTAC linker
Bim BH3, Peptide IV is a novel and potent 26-residue peptide