(R)-Verapamil HCl

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price
250mg	Get quote
500mg	Get quote
1g	Get quote

: [email protected] [email protected]

Cat #: V40744 CAS #: 38176-02-2 Purity ≥ 99%

Description: (R)-Verapamil HCl, the hydrochloride salt of Verapamil R-isomer, is a novel and potent P-Glycoprotein (MRP1, efflux pump in multidrug resistant tumor cells) inhibitor. It blocks MRP1 mediated transport, leading to chemosensitization of MRP1-overexpressing cells to anticancer drugs.

Top Publications Citing Invivochem Products

Product Catalog 2022

Guide to Product Handling

Publications Citing InvivoChem Products

Product Promise

Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	491.06
Molecular Formula	C₂₇H₃₉ClN₂O₄
CAS No.	38176-02-2
Synonyms	(R)Verapamil HCl

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.0364 mL	10.1821 mL	20.3641 mL	40.7282 mL
5mM	0.4073 mL	2.0364 mL	4.0728 mL	8.1456 mL
10mM	0.2036 mL	1.0182 mL	2.0364 mL	4.0728 mL
20mM	0.1018 mL	0.5091 mL	1.0182 mL	2.0364 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.