Skatole is a bioactive compound produced by intestinal bacteria. It can regulate intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
RSM-932A is a novel and potent anticancer drug.
PD-160170 is a novel, potent and selective non-peptide NPY1-R antagonist
HHQ (2-Heptylquinoline-4(1H)-one) is a novel and potent antagonist of PqsR.
Echinocystic acid is a naturally occurring pentacyclic triterpene found in the fruits of Gleditsia sinensis Lam with antioxidant, anti-inflammatory and anticancer pactivities.
Phentolamine Analogue 1 is a phentolamine analog and a nonselective alpha-adrenergic antagonist. J.A. Parihar, et al. Alkylation of diphenylamines with chloroacetonitrile: a new entry to phentolamine analogues. Journal of Chemical Research (2004), (3), 220-222.
Risedronate acid (Risedronate; Actonel) is a novel and potent pyridinyl biphosphonate which acts by inhibiting osteoclast-mediated bone resorption. Risedronate is prepared as its sodium salt risedronate sodium, is often used as a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget’s disease of bone.
CarfecillinSodium (BRL-3475; BRL3475; Carbenicillin Phenyl Sodium), the phenyl ester and sodium salt form of Carbenicillin, is a semi-synthetic penicillin and a prodrug of carboxybenicillin with improved oral absorption. Upon oral administration, it is broken into the active antibiotic in the GI tract. It is used for urinary tract infections.
Withanolide B is a natural bioactive compound found in W. somnifera with anti-aging, neuroprotective, anti-arthritic, and anti-cancer effects. It promotes osteogenic differentiation of hBMSCs via regulating ERK1/2 and Wnt/β-catenin signaling pathways.
Ipatasertib hydrochloride (GDC-0068) is a novel, potent, orally bioavailable, ATP-competitive and highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM in cell-free assays, it showed 620-fold selectivity over PKA. GDC-0068 is used for the treatment of human cancers. The PI3K-AKT pathway regulates cell growth, survival and tumorigenesis. GDC-0068 binds to and […]