Arimoclomol, formerly known as BRX-220, is a heat shock protein amplifier, and is potentially useful for the treatment of Niemann-Pick disease type C (NP-C).

Debio 0932 (also known as CUDC-305) is a novel, potent and orally bioactive HSP90 (heat shock protein 90) inhibitor with IC50s of 100 and 103 nM for HSP90α and HSP90β, respectively.

JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor, which binds tightly to a conserved site on Hsp70 and disrupts the Hsp70-Bag3 interaction.

Palmitic acid (PA) is a long-chain (16-carbon chain) saturated fatty acid commonly found in both animals and plants.

CCT-251236, a chemical probe bisamide, is a novel, potent and orally bioavailable Pirin Ligand identified from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen (IC50 of 19 nM for inhibition of HSF1-mediated HSP72 induction).

HSP70-IN-1 is a novel and potent heat shock protein (HSP) inhibitor.

Chetomin (also called NSC289491, BRN0077366), an antibiotic metabolite of chaetomium cochliodes and a natural product isolated from Chaetomium species which has anticancer, antibacterial and antifungal properties, is an inhibitor of HIF-1 which weakens transcription of HIF-1, and disrupts the binding of HIF-1α and HIF-2α to p300 at low nanomolar concentrations.

MKT-077 is an inhibitor of mitochondrial hsp70 family member mortalin (mot-2), causing the selective death of cancer cells.

Paeoniflorin (Peoniflorin), a glycoside, is a herbal constituent extracted from the root of Paeonia albiflora Pall.

ML346 (CID767276) is a novel and potent activator of heat shock protein 70 (Hsp70) (EC50 = 4600 nM in HeLa cell toxicity assay).