Molsidomine is an orally bioactive and long acting vasodilator acting as an NO donor and annexin A2 inhibitor.

Dasatinib N-oxide is a major and N-oxidated metabolite of Dasatinib (BMS354825; Sprycel), which is an approved anticancer drug acting as a dual Bcr-Abl and Src kinase inhibitor.

Urolithin A is a microbial metabolite of ellagic acid in the gut and an inducer of mitophagy.

Ivabradine metabolite N-Demethyl Ivabradine hydrochloride is the N-demethylated metabolite of ivabradine (S-16257; S16257; S 16257; Corlentor; Coralan; Procoralan; Coraxan; Ivabid; Bradia), which is a cardiac pacemaker current (If) inhibitor and a medication approved in 2015 for the management of stable heart-related chest pain and heart failure.

Berberrubine chloride is an active metabolite of berberine with anti-inflammatory activity.

Acetaminophen metabolite 3-hydroxy-acetaminophen is a metabolite of Acetaminophen (Paracetamol, Tylenol; a pain reliever and fever reducer).

Duloxetine metabolite Para-Naphthol Duloxetine is a metabolite of Duloxetine, which is a serotonin-norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depressive disorder and generalized anxietydisorder (GAD), fibromyalgia and neuropathic pain.

4-Hydroxymephenytoin is a CYP2C19-mediated metabolite of mephenytoin which is an antiepileptic drug with anticonvulsant activities.

4′-Hydroxydiclofenac is an active CYP2C9-mediated metabolite of diclofenac which is potent nonsteroidal anti-inflammatory drug (NSAID) and a Cox-2 inhibitor.

Niraparib metabolite M1 is a carboxylic acid metabolite of niraparib (MK4827; Zejula), which is a PARP1/2 inhibitor approved for cancer treatment.