Procarbazine HCl (formerly NSC77213; Ro4-6467; CB-400-497; PCB; PCZ; Matulane; Natulanar), the hydrochloride salt form of procarbazine, is an anticancer chemotherapeutic medication approved for the treatment of Hodgkin’s lymphoma and certain brain cancers.

Adenine (formerly NSC 14666; NSC-14666; NSC14666; 6-Aminopurine; Vitamin B4), one of the four chemical/nucleobases in DNA, is a purine derivative and a nucleobase with a variety of functions in biochemistry.

Chlorambucil (CB-1348; WR-139013; CB 1348; WR 139013; chloraminophen; Chlorbutin; chlorbutine; chlorbutinum; Leukersan; Leukoran) is an approved antitumor medication mainly used in the treatment of chronic lymphocytic leukemia.

Floxuridine (5-fluorodeoxyuridine; Deoxyfluorouridine, FDUR, NSC-27640; FdUrD; fluorodeoxyuridine; fluorouridine deoxyribose; FUDF; 5FUDR; FUdR; WR138720) is an antimetabolite anticancer drug approved for the treatment of colon carcinoma and colorectal cancer that has metastasized to the liver.

Streptozotocin (also known as NSC-85998, STZ, Streptozotocin; U 9889) is a glucosamine-nitrosourea derivative and a potent DNA-methylating agent with IC50s of 11.7, 904 and 1024 μg/mL in HL60, K562 and C1498 cells respectively.

BMH-21 (BMH 21; BMH21) is a novel and potent DNA intercalator with potential antineoplastic activity.

Didox (also known as NSC-324360) is a novel, potent and synthetic ribonucleotide reductase (RR) inhibitor.

SCR7 (SCR-7; SCR 7) is a potent and selective inhibitor of DNA Ligase IV with potential anticancer activity.

Dacarbazine (formerly also known as DTIC, DTIC-Dome; WR-139007; Asercit; Dacatic; Deticene) is an antitumor chemotherapeutic drug approved by FDA in the 1970s for the treatment of various cancers, including advanced melanoma (major use), Hodgkin lymphoma, sarcoma, and islet cell carcinoma of the pancreas.

ML216 (formerly known as CID-49852229) is a novel potent inhibitor of the Bloom’s syndrome protein (BLM) helicase which is responsible for DNA unwinding activity.