BMH-21

This product is for research use only, not for human use. We do not sell to patients.

BMH-21
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$590In Stock
500mg$950In Stock
1g$1425In Stock

Cat #: V1435 CAS #: 896705-16-1 Purity ≥ 98%

Description: BMH-21 (BMH 21; BMH21) is a novel and potent DNA intercalator with potential antineoplastic activity.

References: Colis L, et al. DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response. Oncotarget. 2014 Jun 30;5(12):4361-9.

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Product Promise

Promise
Molecular Weight (MW)360.41
Molecular FormulaC21H20N4O2
CAS No.896705-16-1
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 5 mg/mL (13.9 mM)r
Water: <1 mg/mLr
Ethanol: 2 mg/mL (5.5 mM)
SynonymsBMH 21; BMH-21; BMH21;
ProtocolIn VitroBMH-21 binds ribosomal DNA and inhibits Pol I transcription.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.7746 mL13.8731 mL27.7462 mL55.4924 mL
5mM0.5549 mL2.7746 mL5.5492 mL11.0985 mL
10mM0.2775 mL1.3873 mL2.7746 mL5.5492 mL
20mM0.1387 mL0.6937 mL1.3873 mL2.7746 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.