Tranylcypromine hemisulfate, also known as 2-PCPA, is a nonselective and irreversible monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.
Tranylcypromine HCl (also known as SKF385 HCl; 2-PCPA) is discontinued.
Paeonol (also known as NSC-401442; NSC401442; Peonol), a naturally occurring phenolic compound isolated from Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum which are used in traditional Chinese herbs/medicines.
Safinamide Mesylate (formerly PNU-151774E, FCE-28073; NW-1015; EMD-1195686; Xadago), the mesylate salt of Safinamide, is a selective and reversible inhibitor of MAO-B with anti-PD (Parkinson’s diseas) effects.
Dorzolamide HCl (also known as MK-507; L-671152 HCl; L671152; MK507; trade name Trusopt), an anti-glaucoma agent and CAI (carbonic anhydrase inhibitors), is a water-soluble and potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively.
Sennoside A (formerly also known as NSC112929; NSC-112929), used as a laxative and an anti-constipation agent, is a naturally occurring dianthrone glycoside compound isolated from Rhei Rhizoma and senna leaf.
Safinamide (formerly known as EMD-1195686; FCE-26743; EMD1195686; FCE26743; trade name: Xadago) is an FDA approved anti-PD ( Parkinson’s disease) drug.
Topiramate (MCN-4853; RWJ-17021; HSDB-7531; Tipiramato; Topax) is an approved anticonvulsant (antiepilepsy) drug used to treat certain types of seizures.
Methazolamide (Neptazaneat; Naptazane; CL-8490; CL8490) is a highly potent and selective inhibitor of carbonic anhydrase (CAI) with important biological activity.
Dorzolamide (L671152; MK507; L671152; MK507; Trusopt) is a CAI (carbonic anhydrase inhibitors) approved for use as an anti-glaucoma agent.