Tranylcypromine (2-PCPA) HCl
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 1g | $290 | Check With Us |
| 2g | $520 | Check With Us |
| 5g | $880 | Check With Us |
: Cat #: V0903 CAS #: 1986-47-6 Purity ≥ 98%
Description: Tranylcypromine HCl (also known as SKF385 HCl; 2-PCPA) is discontinued.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 169.65 |
|---|---|
| Molecular Formula | C9H12ClN |
| CAS No. | 1986-47-6 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 33 mg/mL (194.5 mM)r |
| Water: N/Ar | |
| Ethanol: 33 mg/mL (194.5 mM) | |
| Synonyms | SKF-385 HCl; SKF 385 HCl; 2-PCPA Hydrochloride; SKF385 HCl; 2-PCPA HCl; Tranylcypromine hydochloride; Tranylcypromine HCl |
| Protocol | In Vitro | Tranylcypromine hydrochlorid (2 μM; 3 h) shows a specific derepression of OCT4 transcription. Tranylcypromine hydrochlorid (50 μM-5 mM; 1 h or 12-14 h) inhibits histone and nucleosomal demethylation. |
|---|---|---|
| In Vivo | Tranylcypromine hydrochlorid (3 mg/kg; i.p. once daily for 3 days) decreases LPS-mediated microglial activation and proinflammatory cytokine COX-2 and IL-6 levels in wild-type mice. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 5.8945 mL | 29.4724 mL | 58.9449 mL | 117.8898 mL |
| 5mM | 1.1789 mL | 5.8945 mL | 11.7890 mL | 23.5780 mL |
| 10mM | 0.5894 mL | 2.9472 mL | 5.8945 mL | 11.7890 mL |
| 20mM | 0.2947 mL | 1.4736 mL | 2.9472 mL | 5.8945 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.