Metformin HCl is a hypoglycemic medication used in the treatment of type 2 diabetes (non-insulin-dependent diabetes mellitus).

Peiminine is a novel and potent anti-inflammatory compound.

QX77 is a novel and potent chaperone-mediated autophagy (CMA) activator.

ROC-325 is a novel, potent and orally bioactive autophagy inhibitor with potent anticancer activity.

Elaiophylin (also known as Azalomycin-B) shows antiprotozoal activity against Plasmodium falciparum K1a and Trypanosoma brucei brucei GUTat 3.1 strains with IC50 of 0.36 μM and 0.45 μM, respectively.

Niclosamide (Clonitralide, Fenasal, BAY-2353, NSC-178296, WR-46234) is a potent and orally bioavailable chlorinated salicylanilide analog with anthelmintic and potential antineoplastic activity.

SBI-0206965 is a cell permeable and selective autophagy kinase ULK1 inhibitor with IC50 of 108 nM, it is about 7-fold selectivity over ULK2.

Carbamazepine (formerly also known as CBZ, NSC-169864, Carbatrol; Tegretol, Epitol), an approved anticonvulsant drug, is a potent sodium channel blocker with IC50 of 131 μM in rat brain synaptosomes.

Autophinib is a novel and potent autophagy inhibitor, which inhibits starvation-induced or rapamyc induced autophagy.

Dexamethasone (also known as DHAP; Hexadecadrol; Prednisolone F)) is a potent synthetic glucocorticoid class of steroid drugs, and an interleukin receptor modulator with anti-inflammatory and immunosuppressive activities.