Ivabradine HCl (Corlentor; Corlanor; Coraxan; Ivabid; Procoralan; Coralan; S16257; S 16257; S-16257; Bradia), the hydrochloride salt of Ivabradine, is a novel and potent cardiac pacemaker current (If) inhibitor with antianginal effects.
Batefenterol (formerly known as GSK961081 and TD-5959) is a novel, potent and selective muscarinic receptor antagonist and β2-adrenoceptor agonist; it displays high affinity for hM2, hM3 muscarinic and hβ2-adrenoceptor with Ki values of 1.4, 1.3 and 3.7 nM, respectively.
ARC 239 dihydrochloride is a potent and selective α2B adrenoceptor antagonist.
Nebivolol (also known as R-65824) potently and selectively inhibits β1-adrenoceptor with IC50 of 0.8 NM.
Oxymetazoline HCl (Rhinofrenol; Afrin; Ocuclear; Drixine; Nezeril; Sinerol; Hazol; Nafrine; Navasin), the hydrochloride salt of oxymetazoline, is an imidazole-based α1 and α2 adrenergic receptor agonist.
Naftopidil (BM-15275; KT611; BM15275; KT611; Flivas) is a selective α1-adrenergic receptor antagonist that has been approved for the treatment of BPH-benign prostatic hyperplasia.
Doxazosin mesylate (formerly UK-33274; UK 33274; trade names Cardura), the mesylate salt of Doxazosin which is a quinazoline-derivative, is a potent and selective antagonist of postsynaptic α1-adrenergic receptors (so called alpha-blockers) with anti-hypertensive effects.
Bambuterol HCl (Bambec; Oxeol; KWD-2183l; UNII-Y1850G1OVC), the hydrochloride salt of Bambuterol which is a prodrug of terbutaline, is a potent and long acting beta-adrenoceptor agonist (LABA) that was approved (outside the US) for use in the treatment of asthma.
Labetalol HCl (ch15719W; AH5158; Normodyne, Albetol, Trandate, Apo-Labetalol, Dilevalol), the hydrochloride salt of Labetalol, is a competitive and dual antagonist of alpha1-adrenergic and beta-adrenergic receptors with potential antihypertensive properties.
Naftopidil 2HCl (BM-15275; KT-611; BM15275; KT611; Flivas), the dihydrochloride salt of Naftopidil, is a potent and selective α1-adrenergic receptor antagonist with antihypertensive effects.