Trazodone HCl (Beneficat, KB 831, KB831, AF 1161, AF1161), the hydrochloride salt of Trazodone, is an approved antidepressant drug of the class of serotonin receptor antagonists and reuptake inhibitors (SARI) with the potential for treatment of anxiety disorders.
Agomelatine (S20098; AGO-178; S-20098; AGO178; Valdoxan, Melitor, Thymanax) is a potent and specific agonist of MT1 and MT2 receptors with anti-depressive activity.
Pindolol (known also as LB-46), a nonselective β-blocker with partial beta-adrenergic receptor agonist activity, is an aryloxypropanolamine derivative with antihypertensive property.
MK-0893 (CRA1; MK0893) is a novel, potent and selective glucagon receptor antagonist with an IC50 of 6.6 nM.
Desvenlafaxine Succinate (formerly WY45233; WY 45233; O-desmethylvenlafaxine; trade name Pristiq, Desfax), the succinate salt of Desvenlafaxine which is an approved antidepressant drug, is a novel and potent serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively.
Intepirdine (formerly GSK-742457; RVT-101; SB742457; SB 742457; GSK742457; SB-742457; RVT 101) is a potent and highly selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects.
Ansofaxine hydrochloride (LY03005; LPM570065) is a triple reuptake inhibitor; inhibits serotonin, dopamine and norepinephrine reuptake with IC50 of 723, 491 and 763 nM, respectively.
Metoclopramide HCl hydrate is a potent and selective dopamine D2 receptor antagonist.
SB269970 HCl (SB 269970; GR125743; GR-125743; SB-269970), the hydrochloride salt form of SB-269970, is a novel and potent 5-HT7 receptor antagonist with antianxiety-like effects.
Lumateperone PTSA salt (ITI-722, ITI-007; Caplyta), the toluenesulfonic acid salt of Lumateperone, is a dual 5HT2A receptor antagonist and dopamine receptor phosphoprotein modulator (DPPM), approved as an atypical antipsychotic in 2019 for the treatment of schizophrenia.